DYF-5/MAK-dependent phosphorylation promotes ciliary tubulin unloading.
Jiang X, Shao W, Chai Y, Huang J, Mohamed MAA, Ökten Z, Li W, Zhu Z, Ou G.
PNAS vol. 119 no. 34
2022
The physiological cargo adaptor of kinesin-2 functions as an evolutionary conserved lockpick.
Cleetus A, Merck G, Mueller-Planitz F, Ökten Z.
PNAS vol. 119 no. 33
2022
Kinesin-2 from C. reinhardtii is an atypically fast and auto-inhibited motor that is activated by heterotrimerization for intraflagellar transport
Punam Sonar, Wiphu Youyen, Augustine Cleetus, Pattipong Wisanpitayakorn, Iman S. Mousavi, Willi L. Stepp, William O. Hancock, Erkan Tüzel, Zeynep Ökten
Current Biology https://doi.org/10.1101/855940
2020
Molecular Underpinnings of Cytoskeletal Crosstalk
Angela Oberhofer, Emanuel Reithmann, Peter Spieler, Willi L Stepp, Dennis Zimmermann, Bettina Schmid, Erwin Frey, Zeynep Ökten
Proc Natl Acad Sci 201917964
2020
Optimal sidestepping of intraflagellar transport kinesins regulates structure and function of sensory cilia.
Xie C, Li L, Li M, Shao W, Zuo Q, Huang X, Chen R, Li W, Brunnbauer M, Ökten Z, Chen L, Ou G.
EMBO J. vol. 39 no.12
2020
Resolving kinesin stepping: one head at a time
Willi L. Stepp & Zeynep Ökten
Life science alliance 2 (5)
2019
Reconstitution reveals motor activation for intraflagellar transport
Mohamed A.A. Mohamed, Willi L. Stepp, Zeynep Ökten
Nature 557, 387–391
2018
Myosin Va’s adaptor protein melanophilin enforces track selection on the microtubule and actin networks in vitro
Angela Oberhofer, Peter Spieler, Yuliya Rosenfeld, Willi L. Stepp, Augustine Cleetus, Alistair N. Hume, Felix Mueller-Planitz, and Zeynep Ökten
PNAS vol. 114 no. 24
2017
Kinesin-2 motors adapt their stepping behaviour for processive transport on axonemes and microtubules
Willi L. Stepp, Georg Merck, Felix Mueller-Planitz, Zeynep Ökten
EMBO Rep 18, 1947–1956
2017
A non-mitotic CENP-E homolog in Dictyostelium discoideum with slow motor activity
Kösem S, Ökten Z, Ho TH, Trommler G, Koonce MP, Samereier M, Müller-Taubenberger A.
Biochem Biophys Res Commun. vol. 431 no.3
2013
In vitro reconstitution of an mRNA-transport complex reveals mechanisms of assembly and motor activation.
Heym RG, Zimmermann D, Edelmann FT, Israel L, Ökten Z, Kovar DR, Niessing D.
J Cell Biol. vol. 203 no.6
2013
Torque generation of Kinesin motors is governed by the stability of the neck domain
M. Brunnbauer, R. Dombi, T. H. Ho, M. Schliwa, M. Rief, Z. Ökten
Molecular Cell 2, 147-58
2012
Diffusion of myosin V on microtubules: a fine-tuned interaction for which E-hooks are dispensable
D. Zimmermann, B. Abdel Motaal, L. Voith von Voithenberg, M. Schliwa, Z. Ökten
PLoS One 6(9):e25473
2011
How kinesin-2 forms a stalk
M. Vukajlovic, H. Dietz, M. Schliwa, Z. Ökten
Mol Biol Cell 22(22):4279-87
2011
The Lever Arm Effects a Mechanical Asymmetry of the Myosin-V-Actin Bond
J. C. M. Gebhardt, Z. Ökten, M. Rief
Biophysical Journal 98:277-281
2010
Regulation of a heterodimeric kinesin-2 through an unprocessive motor domain that is turned processive by its partner
M. Brunnbauer, F. Mueller-Planitz, S. Kösem, T. H. Ho, R. Dombi, J. C. M. Gebhardt, M. Rief, Z. Ökten
Proc Natl Acad Sci U S A 107:10460-10465
2010
Molecular motors: A step dissected
Z. Ökten, M. Schliwa
Nature 450(7170):625-6
2007
Single molecule high-resolution colocalization of Cy3 and Cy5 attached to macromolecules measures intramolecular distances through time
L. S. Churchman, Z. Ökten, R. S. Rock, J. F. Dawson, J. A. Spudich
Proc Natl Acad Sci U S A 102(5):1419-23
2005
Myosin VI walks hand-over-hand along actin
Z. Ökten, L. S. Churchman, R. S. Rock, J. A. Spudich
Nat Struct Mol Biol 11(9):884-7
2004